Anti-amphiphysin encephalitis: Expanding the clinical spectrum.

ABSTRACT:

Objective

An analysis of the clinical features of autoimmune encephalitis accompanied by anti-amphiphysin antibodies.

Methods

The data of encephalitis patients with anti-amphiphysin antibodies were retrospectively evaluated, including demographics, neurological and laboratory findings, imaging, treatment, and prognostic predictions.

Results

Ten patients aged between 29 and 78 years (median age 52 years) were included. The male: female ratio was 4:6. Limbic encephalitis was found in nine patients while epileptic seizures were present in seven patients. All patients showed anti-amphiphysin antibody positivity in sera while one ninth was positive for CSF antibody. The EEG findings were abnormal, including reductions in background activity, and the presence of diffuse slo

SUBMITTER: Sun Y 

PROVIDER: S-EPMC10113538 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature