Radiosurgical treatment of solitary brain metastases using virtual cones with a standard multileaf collimator.

ABSTRACT:

Purpose

The virtual cone has been previously introduced as a novel technique for generating small, spherical dose distributions using a high-definition multileaf collimator (MLC) for functional radiosurgery applications. There has been no reported investigation into adapting this technique to a standard MLC for the treatment of solitary intracranial metastases as an alternative to physical stereotactic cones. This study characterizes the virtual cone technique adapted to a standard 5 mm leaf-width MLC (VC_SD ).

Methods

VC_SD dose distributions using MLC leaf gaps of 2-5 mm were generated and isodose sphericity metrics, peak dose gradients, optimal normalization ranges, and achievable field widths were compared to those of 5.0-12.5 mm diameter physical con

SUBMITTER: Lobb E 

PROVIDER: S-EPMC10113701 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature