Versatility of Stenotrophomonas maltophilia: Ecological roles of RND efflux pumps.

ABSTRACT: S. maltophilia is a widely distributed bacterium found in natural, anthropized and clinical environments. The genome of this opportunistic pathogen of environmental origin includes a large number of genes encoding RND efflux pumps independently of the clinical or environmental origin of the strains. These pumps have been historically associated with the uptake of antibiotics and clinically relevant molecules because they confer resistance to many antibiotics. However, considering the environmental origin of S. maltophilia, the ecological role of these pumps needs to be clarified. RND efflux systems are highly conserved within bacteria and encountered both in pathogenic and non-pathogenic species. Moreover, their evolutionary origin, conservation and multiple copies in bacteri

SUBMITTER: Chauviat A 

PROVIDER: S-EPMC10113797 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature