Accuracy of deformable image registration-based intra-fraction motion management in Magnetic Resonance-guided radiotherapy.

ABSTRACT:

Background and purpose

Intra-fraction motion management is key in Stereotactic Ablative Radiotherapy (SABR) gated delivery. This study assessed the accuracy of automatic tumor segmentation in the delivery of MR-guided radiotherapy (MRgRT) by comparing it to manual delineations performed by experienced observers.

Materials and methods

Twenty patients previously treated with MR-guided SABR for thoracic and abdominal tumors were included. Five observers with at least two years of experience in MRgRT manually delineated the gross tumor volume (GTV) for 20 patients on 240 frames of a cine MRI on a sagittal plane. Deformable Image Registration (DIR) based GTV contours were propagated using four different algorithms from a reference frame to subsequent frames.Geometrical analysis b

SUBMITTER: Palacios MA 

PROVIDER: S-EPMC10113900 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature