Effects of ageing on aortic hemodynamics measured by 4D-flow MRI: a case series.

ABSTRACT:

Background

It has been demonstrated that the rate of aortic dilatation is influenced by alteration of aortic hemodynamics, such as normalized flow displacement (FD_N) and wall shear stress (WSS). However, the effects of ageing on aortic hemodynamics have not yet been described.

Case summary

4D-Flow MRI derived aorta hemodynamics were derived in the ascending aorta of a patient with ascending aortic aneurysm (mean ± standard deviation: 46 ± 1 mm) and a healthy volunteer (aortic diameter 30 ± 1 mm) with long-term follow-up of ten and eight years, respectively. At all timepoints, compared to the healthy volunteer, the patient demonstrated higher magnitudes of FD_N (7% ± 1% vs. 3% ± 1%) and WSS angle (36° ± 3° vs. 24° ± 6°), and lower WSS magnitude (565 ± 100

SUBMITTER: Juffermans JF 

PROVIDER: S-EPMC10113929 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature