Disease progression and costs at the 3-year follow-up of the GERAS-US study.

ABSTRACT:

Introduction

GERAS-US prospectively characterized clinical and economic outcomes of early symptomatic Alzheimer's disease (AD). Societal cost changes were examined in amyloid-positive patients with mild cognitive impairment due to AD (MCI) and mild dementia due to AD (MILD).

Methods

Cognition, function, and caregiver burden were assessed using Mini-Mental State Examination (MMSE), Cognitive Function Index (CFI), and Zarit Burden Interview, respectively. Costs are presented as least square mean for the overall population and for MCI versus MILD using mixed model repeated measures.

Results

MMSE score and CFI worsened. Total societal costs (dollars/month) for MCI and MILD, respectively, were higher at baseline ($2430 and $4063) but steady from 6 ($1977 and $3032) to 36 m

SUBMITTER: Chandler JM 

PROVIDER: S-EPMC10113935 | biostudies-literature | 2023 Apr-Jun

REPOSITORIES: biostudies-literature