Longitudinal characterization of determinants associated with obesogenic growth patterns in early childhood.

ABSTRACT:

Background

Longitudinal assessment of the determinants of obesogenic growth trajectories in childhood can suggest appropriate developmental windows for intervention.

Methods

Latent class growth mixture modelling was used to identify body mass index (BMI) z-score trajectories from birth to age 6 years in 994 children from a prospective mother-offspring cohort (Chinese, Indian and Malay ethnicities) based in Singapore. We evaluated the early-life determinants of the trajectories as well as their associations with cardiometabolic risk markers at age 6 years.

Results

Five BMI z-score trajectory patterns were identified, three within the healthy weight range, alongside early-acceleration and late-acceleration obesogenic trajectories. The early-acceleration pattern was char

SUBMITTER: Michael N 

PROVIDER: S-EPMC10114026 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature