Mendelian randomization analysis for attention deficit/hyperactivity disorder: studying a broad range of exposures and outcomes.

ABSTRACT:

Background

Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder caused by a combination of genetic and environmental factors and is often thought as an entry point into a negative life trajectory, including risk for comorbid disorders, poor educational achievement or low income. In the present study, we aimed to clarify the causal relationship between ADHD and a comprehensive range of related traits.

Methods

We used genome-wide association study (GWAS) summary statistics for ADHD (n = 53 293) and 124 traits related to anthropometry, cognitive function and intelligence, early life exposures, education and employment, lifestyle and environment, longevity, neurological, and psychiatric and mental health or personality and psychosocia

SUBMITTER: Soler Artigas M 

PROVIDER: S-EPMC10114062 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature