Adherence to guideline-directed medical therapy and 3-year clinical outcome following acute myocardial infarction.

ABSTRACT:

Aims

Despite the well-established clinical benefits and strong recommendations in clinical guidelines, adherence to guideline-directed medical therapy (GDMT) is known to be insufficient. We investigated the adherence to GDMT and its impact on the 3-year clinical outcomes in patients with acute myocardial infarction (AMI).

Methods and results

Source data were obtained from KAMIR-NIH, a Korean multi-centre observational registry. GDMT was defined according to the ACC/AHA Class I recommendations. Adherence to GDMT was assessed at discharge and every year thereafter. The differences in clinical characteristics between patients receiving and those not receiving GDMT were adjusted using propensity score matching (PSM) or inverse probability of treatment weighting (IPTW). The prima

SUBMITTER: Lee SH 

PROVIDER: S-EPMC10114289 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature