Tracking Fluorine during Aqueous Photolysis and Advanced UV Treatment of Fluorinated Phenols and Pharmaceuticals Using a Combined ¹⁹F-NMR, Chromatography, and Mass Spectrometry Approach.

ABSTRACT: Fluorine incorporation into organic molecules has increased due to desirable changes in the molecular physiochemical properties. Common fluorine motifs include: aliphatic fluorines and -CF₃, or -F containing groups bonded directly onto an aromatic (Ar-CF₃ and Ar-F) or heteroaromatic ring. Photolysis of these compounds, either in natural or engineered systems, is a potential source of new fluorinated byproducts. Given the potential persistence and toxicity of fluorinated byproducts, monitoring of product formation during photolysis of various fluorinated motifs is needed. ¹⁹F-NMR is a means to detect and quantify these species. Ar-CF₃ and Ar-F model compounds (2-, 3-, and 4-(trifluoromethyl)phenol, 2-, 3-, 4-fluorophenol, and 2,6-, 3,5-difluorophe

SUBMITTER: Bhat AP 

PROVIDER: S-EPMC10114624 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature