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Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development.


ABSTRACT: Genome and cell size are strongly correlated across species1,2,3,4,5,6 and influence physiological traits like developmental rate.7,8,9,10,11,12 Although size scaling features such as the nuclear-cytoplasmic (N/C) ratio are precisely maintained in adult tissues,13 it is unclear when during embryonic development size scaling relationships are established. Frogs of the genus Xenopus provide a model to investigate this question, since 29 extant Xenopus species vary in ploidy from 2 to 12 copies (N) of the ancestral frog genome, ranging from 20

SUBMITTER: Miller KE 

PROVIDER: S-EPMC10115129 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature