Residential proximity to agriculture and risk of childhood leukemia and central nervous system tumors in the Danish national birth cohort.

ABSTRACT:

Background

Living in an agricultural area or on farms has been associated with increased risk of childhood cancer but few studies have evaluated specific agricultural exposures. We prospectively examined residential proximity to crops and animals during pregnancy and risk of childhood leukemia and central nervous system (CNS) tumors in Denmark.

Methods

The Danish National Birth Cohort (DNBC) consists of 91,769 pregnant women (96,841 live-born children) enrolled in 1996-2003. For 61 childhood leukemias and 59 CNS tumors <15 years of age that were diagnosed through 2014 and a ~10% random sample of the live births (N = 9394) with geocoded addresses, we linked pregnancy addresses to crop fields and animal farm locations and estimated the crop area (hectares [ha]) and number of a

SUBMITTER: Patel DM 

PROVIDER: S-EPMC10115138 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature