Dissecting eustachian tube dysfunction: From phenotypes to endotypes.

ABSTRACT:

Objective

A broad spectrum of complaints, symptoms and manifestations has been assigned to Eustachian tube (ET) dysfunction (ETD). While such presentations may manifest as ETD phenotypes, underlying mechanisms are defined as endotypes. Our goal is to develop a diagnostic approach to differentiate the endotypes and guide clinicians in the workup and selection of treatments targeting the mechanism of ETD.

Study design

Retrospective.

Setting

Tertiary care.

Subjects and methods

Children and adults with suspected ETD were evaluated with a thorough examination, otomicroscopy, otoendoscopy, trans-nasal videoendoscopy and testing of passive and active ET dilatory properties. Degree of weakness in soft palate elevation and ET orifice widening (muscular weakness, ETD-M),

SUBMITTER: Alper CM 

PROVIDER: S-EPMC10115295 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature