Clinical frailty scale as a predictor of outcome in elderly patients affected by moderate or severe traumatic brain injury.

ABSTRACT:

Background

Older age is a well-known risk factor for unfavorable outcome in traumatic brain injury (TBI). However, many older people with TBI respond well to aggressive treatments, suggesting that chronological age and TBI severity alone may be inadequate prognostic markers. Frailty is an age-related homeostatic imbalance of loss of physiologic and cognitive reserve resulting in both limitation in autonomy of activities of daily living and vulnerability to adverse events. We hypothesized that frailty would be associated with 6-month adverse functional outcome in older people affected by moderate or severe TBI.

Methods

This was a single-center prospective observational study. We enrolled consecutive patients aged ≥65 years after TBI with Glasgow Coma Scale ≤13 and admitted to

SUBMITTER: Zacchetti L 

PROVIDER: S-EPMC10116041 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature