Cryptic Chemical Variation in a Marine Red Alga as Revealed by Nontargeted Metabolomics.

ABSTRACT: Many marine algae occupy habitats that are dark, deep, or encrusted on other organisms and hence are frequently overlooked by natural product chemists. However, exploration of less-studied organisms can lead to new opportunities for drug discovery. Genetic variation at the individual, species, genus, and population levels as well as environmental influences on gene expression enable expansion of the chemical repertoire associated with a taxonomic group, enabling natural product exploration using innovative analytical methods. A nontargeted LC-MS and ¹H NMR spectroscopy-based metabolomic study of 32 collections of representatives of the calcareous red algal genus Peyssonnelia from coral reef habitats in Fiji and the Solomon Islands revealed significant correlations between

SUBMITTER: Khatri Chhetri B 

PROVIDER: S-EPMC10116502 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature