Real-world burden and treatment of chronic rhinosinusitis in Japan: A retrospective claims database analysis.

ABSTRACT:

Objectives

Chronic rhinosinusitis (CRS) is a heterogeneous disease, which can be subdivided into CRS with (CRSwNP) or without (CRSsNP) nasal polyps. An intractable form of CRSwNP that is associated with an eosinophil-dominant inflammatory cell infiltration (eosinophilic CRS) has become more prevalent in Japan. There is currently limited information on the burden of CRS in Japan and treatment approaches used in real-world practice.

Methods

This retrospective, observational, comparative cohort study used information from the Japanese JMDC insurance claims database (study period April 1, 2015, to March 31, 2020). A CRS cohort was identified and matched with a control group without CRS. The primary objective was to clarify disease burden and treatment approaches by comparing com

SUBMITTER: Yoshikawa M 

PROVIDER: S-EPMC10116956 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature