Altered cerebral blood flow in older adults with Alzheimer's disease: a systematic review.

ABSTRACT: The prevalence of Alzheimer's disease is projected to reach 13 million in the U.S. by 2050. Although major efforts have been made to avoid this outcome, so far there are no treatments that can stop or reverse the progressive cognitive decline that defines Alzheimer's disease. The utilization of preventative treatment before significant cognitive decline has occurred may ultimately be the solution, necessitating a reliable biomarker of preclinical/prodromal disease stages to determine which older adults are most at risk. Quantitative cerebral blood flow is a promising potential early biomarker for Alzheimer's disease, but the spatiotemporal patterns of altered cerebral blood flow in Alzheimer's disease are not fully understood. The current systematic review compiles the findings of 81 origi

SUBMITTER: Swinford CG 

PROVIDER: S-EPMC10117447 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature