Phylogenetic diversity of core rumen microbiota as described by cryo-ET.

ABSTRACT: Microbial taxonomy is critical for describing ecosystem composition, yet the link between taxonomy and properties of microbes, such as their cellular architecture, remains poorly defined. We hypothesized that the cellular architecture represents microbial niche adaptation. We used cryo-electron microscopy and tomography to analyze microbial morphology in order to associate cellular architecture with phylogeny and genomic contents. As a model system, we chose the core rumen microbiome and imaged a large isolate collection covering 90% of its richness at the order level. Based on quantifications of several morphological features, we found that the visual similarity of microbiota is significantly related to their phylogenetic distance. Up to the Family level, closely related microbes h

SUBMITTER: Wimmer BH 

PROVIDER: S-EPMC10117717 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature