Should we treat pediatric radiologically isolated syndrome? An 18-year follow-up case report.

ABSTRACT:

Background

Radiologically isolated syndrome (RIS) describes asymptomatic individuals with incidental radiologic abnormalities suggestive of multiple sclerosis (MS). Much of RIS literature is about adult-onset cases. Treatment of RIS is controversial, especially in pediatric age, but early treatment in selected patients might improve long-term outcomes.

Case presentation

We report a single RIS patient who followed up for 18 years in our MS center. At first, she was only monitored with follow-up MRIs. Then, as the lesion load increased, she was treated with a first-line disease-modifying treatment (DMT) reaching MRI stability.

Conclusion

This report highlights how treatment can be an appropriate choice in pediatric forms of RIS.

SUBMITTER: Barbuti E 

PROVIDER: S-EPMC10117757 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature