Ontology highlight
ABSTRACT:
SUBMITTER: Malekos E
PROVIDER: S-EPMC10118063 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Malekos Eric E Carpenter Susan S
Trends in immunology 20220811 9
Next-generation sequencing (NGS) technologies have greatly expanded the size of the known transcriptome. Many newly discovered transcripts are classified as long noncoding RNAs (lncRNAs) which are assumed to affect phenotype through sequence and structure and not via translated protein products despite the vast majority of them harboring short open reading frames (sORFs). Recent advances have demonstrated that the noncoding designation is incorrect in many cases and that sORF-encoded peptides (S ...[more]