Relationship between adiponectin and leptin on osteocalcin in obese adolescents during weight loss therapy.

ABSTRACT:

Objectives

Obesity is a multifactorial disease characterized by the presence of the pro-inflammatory state associated with the development of many comorbidities, including bone turnover marker alterations. This study aimed to investigate the role of the inflammatory state on bone turnover markers in obese adolescents undergoing interdisciplinary weight loss treatment for one year.

Subjects and methods

Thirty four post-pubescent obese adolescents with primary obesity, a body mass index (BMI) greater than > 95th percentile of the CDC reference growth charts, participated in the present investigation. Measurements of body composition, bone turnover markers, inflammatory biomarkers and visceral and subcutaneous fat were taken. Adolescents were submitted to one year of interdisci

SUBMITTER: Campos RMDS 

PROVIDER: S-EPMC10118784 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature