Spontaneous cancer remission after COVID-19: insights from the pandemic and their relevance for cancer treatment.

ABSTRACT: Early in the COVID-19 pandemic, it emerged that the risk of severe outcomes was greater in patients with co-morbidities, including cancer. The huge effort undertaken to fight the pandemic, affects the management of cancer care, influencing their outcome. Despite the high fatality rate of COVID-19 disease in cancer patients, rare cases of temporary or prolonged clinical remission from cancers after SARS-CoV-2 infection have been reported. We have reviewed sixteen case reports of COVID-19 disease with spontaneous cancer reduction of progression. Fourteen cases of remission following viral infections and two after anti-SARS-CoV-2 vaccination. The immune response to COVID-19, may be implicated in both tumor regression, and progression. Specifically, we discuss potential mechanisms which includ

SUBMITTER: Meo C 

PROVIDER: S-EPMC10119533 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature