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Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins.

ABSTRACT: Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that collagen9a1c ( col9a1c ) gene product is essential for the regular arrangement of actinotrichia using col9a1c -knockout zebrafish. Here, we examined the localization pattern of the EGFP-tagged Col9a1c protein in the fins to understand its role in the arrangement of actinotrichia. We found that EGFP-Col9a1c specifically localizes to actinotrichia.

SUBMITTER: Nakagawa H

PROVIDER: S-EPMC10119692 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins.

Nakagawa Hibiki H Aramaki Toshihiro T Kondo Shigeru S Kuroda Junpei J

microPublication biology 20230407

Teleost fish fins are supported by spear-shaped collagen crystals called actinotrichia. Actinotrichia are distributed radially at the distal end of the fins and thought to be necessary for proper formation of the fin and fin-bones. We previously reported that collagen9a1c ( col9a1c ) gene product is essential for the regular arrangement of actinotrichia using col9a1c -knockout zebrafish. Here, we examined the localization pattern of the EGFP-tagged Col9a1c protein in the fin ...[more]

PMID: 37090155

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