Plasmonic Sensing Assay for Long-Term Monitoring (PSALM) of Neurotransmitters in Urine.
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ABSTRACT:
SUBMITTER: Chen WH
PROVIDER: S-EPMC10119978 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
Plasmonic Sensing Assay for Long-Term Monitoring (PSALM) of Neurotransmitters in Urine.
Chen Wei-Hsin WH Wang Wenting W Lin Qianqi Q Grys David-Benjamin DB Niihori Marika M Huang Junyang J Hu Shu S de Nijs Bart B Scherman Oren A OA Baumberg Jeremy J JJ
ACS nanoscience Au 20221224 2
A liquid-based surface-enhanced Raman spectroscopy assay termed PSALM is developed for the selective sensing of neurotransmitters (NTs) with a limit of detection below the physiological range of NT concentrations in urine. This assay is formed by quick and simple nanoparticle (NP) "mix-and-measure" protocols, in which Fe<sup>III</sup> bridges NTs and gold NPs inside the sensing hotspots. Detection limits of NTs from <i>PreNP</i> PSALM are significantly lower than those of <i>PostNP</i> PSALM, wh ...[more]
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