Sweden's first Take-Home Naloxone program: participant characteristics, dose endpoints and predictors for overdose reversals.

ABSTRACT: Opioid overdoses are a growing concern, particularly among people who inject drugs. Sweden, with a comparatively high proportion of drug-related mortality, introduced its first Take-Home Naloxone (THN) program in 2018, at the Stockholm needle and syringe program (NSP). In this study we compare THN participant characteristics regarding refills and overdose reversals as well as investigate predictors associated with number of reversals. We also investigate interventions performed in overdose situations and endpoints for naloxone doses. This was a prospective open inclusion cohort study conducted between January 24th 2018 and March 31st 2022 at the Stockholm NSP. Participants received THN, free of charge, after a training session and provided data regarding drug use and overdose experiences.

SUBMITTER: Holmen E 

PROVIDER: S-EPMC10121425 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature