Combined forced diuresis and late acquisition on [⁶⁸Ga]Ga-PSMA-11 PET/CT for biochemical recurrent prostate cancer: a clinical practice-oriented study.

ABSTRACT:

Objectives

Increased detection of prostate cancer (PCa) recurrences using [⁶⁸Ga]Ga-PSMA-11 PET/CT has been reported by adding forced diuresis or late-phase imaging to the standard protocol. However, the combination of these procedures in the clinical setting is still not standardized.

Methods

One hundred prospectively recruited biochemical recurrent PCa patients were restaged with dual-phase [⁶⁸Ga]Ga-PSMA-11 PET/CT from September 2020 to October 2021. All patients received a standard scan (60 min), followed by diuretics (140 min) and a late-phase abdominopelvic scan (180 min). PET readers with low (n = 2), intermediate (n = 2), or high (n = 2) experience rated (i) standard and (ii) standard + forced diuresis late-phase images in a stepwise fashion accor

SUBMITTER: Bauckneht M 

PROVIDER: S-EPMC10121525 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature