Obesity-related parameters in carriers of some BDNF genetic variants may depend on daily dietary macronutrients intake.

ABSTRACT: Some common single-nucleotide polymorphisms of the brain-derived neurotrophic factor (BDNF) gene have been associated not only with the neurodegenerative diseases but also with some eating disorders. The aim of this study was to assess the possible differences in the obesity-related and glucose metabolism parameters between some BDNF genotypes', that may depend on the daily energy and macronutrients intake. In 484 adult participants we performed the anthropometric measurements, body composition analysis, and body fat distribution. The daily dietary intake was assessed using the 3-day food intake diaries. Blood glucose and insulin concentrations were measured at fasting and during oral glucose tolerance tests. Moreover, the visceral adipose tissue/subcutaneous adipose tissue (VAT/SAT) ratio

SUBMITTER: Miksza U 

PROVIDER: S-EPMC10121660 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature