Clinical feasibility and validation of the accelerated T2 mapping sequence GRAPPATINI in brain imaging.

ABSTRACT:

Rationale and objectives

To prospectively evaluate feasibility and robustness of an accelerated T2 mapping sequence (GRAPPATINI) in brain imaging and to assess its synthetic T2-weighted images (sT2w) in comparison with a standard T2-weighted sequence (T2 TSE).

Material and methods

Volunteers were included to evaluate the robustness and consecutive patients for morphological evaluation. They were scanned on a 3 T MR-scanner. Healthy volunteers underwent GRAPPATINI of the brain three times (day 1: scan/rescan; day 2: follow-up). Patients between the ages of 18 and 85 years who were able to provide written informed consent and who had no MRI contraindications were included. For morphological comparison two radiologists with 5 and 7 years of experience in brain MRI evaluated ima

SUBMITTER: Gruenebach N 

PROVIDER: S-EPMC10121777 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature