Amoxicillin Versus Other Antibiotic Agents for the Treatment of Acute Otitis Media in Children.

ABSTRACT:

Objectives

The objective of the study was to compare the antibiotic treatment failure and recurrence rates between antibiotic agents (amoxicillin, amoxicillin-clavulanate, cefdinir, and azithromycin) for children with uncomplicated acute otitis media (AOM).

Study design

We completed a retrospective cohort study of children 6 months-12 years of age with uncomplicated AOM identified in a nationwide claims database. The primary exposure was the antibiotic agent, and the primary outcomes were treatment failure and recurrence. Logistic regression was used to estimate ORs, and analyses were stratified by primary exposure, patient age, and antibiotic duration.

Results

Among the 1 051 007 children included in the analysis, 56.6% were prescribed amoxicillin, 13.5% were prescri

SUBMITTER: Frost HM 

PROVIDER: S-EPMC10122571 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature