Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.

ABSTRACT: Patients with end-stage renal disease (ESRD) have impaired functional status compared with the general population. We sought to explore the association between Karnofsky Performance Status (KPS) and death/delisting from the kidney transplantation waitlist and whether this association differed by age. Patients listed for single-organ kidney transplantation in the United Network for Organ Sharing/Organ Procurement and Transplantation Network from January 1, 2015, to January 1, 2018, were included. We performed competing-risk regression analyses to determine the association between KPS ("Severely impaired", "Moderately impaired", "Non-impaired") and death/delisting, with deceased-donor kidney transplantation as a competing risk. We tested for interactions between age and KPS on death/delistin

SUBMITTER: Sheshadri A 

PROVIDER: S-EPMC10123007 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature