Establishing thresholds for meaningful within-individual change using longitudinal item response theory.

ABSTRACT:

Purpose

Thresholds for meaningful within-individual change (MWIC) are useful for interpreting patient-reported outcome measures (PROM). Transition ratings (TR) have been recommended as anchors to establish MWIC. Traditional statistical methods for analyzing MWIC such as mean change analysis, receiver operating characteristic (ROC) analysis, and predictive modeling ignore problems of floor/ceiling effects and measurement error in the PROM scores and the TR item. We present a novel approach to MWIC estimation for multi-item scales using longitudinal item response theory (LIRT).

Methods

A Graded Response LIRT model for baseline and follow-up PROM data was expanded to include a TR item measuring latent change. The LIRT threshold parameter for the TR established the MWIC threshol

SUBMITTER: Bjorner JB 

PROVIDER: S-EPMC10123029 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature