The study of selection signature and its applications on identification of candidate genes using whole genome sequencing data in chicken-a review.

ABSTRACT: Chicken is a major source of protein for the increasing human population and is useful for research purposes. There are almost 1,600 distinct regional breeds of chicken across the globe, among which a large body of genetic and phenotypic variations has been accumulated due to extensive natural and artificial selection. Moreover, natural selection is a crucial force for animal domestication. Several approaches have been adopted to detect selection signatures in different breeds of chicken using whole genome sequencing (WGS) data including integrated haplotype score (iHS), cross-populated extend haplotype homozygosity test (XP-EHH), fixation index (F_ST), cross-population composite likelihood ratio (XP-CLR), nucleotide diversity (Pi), and others. In addition, gene enrichment analys

SUBMITTER: Bello SF 

PROVIDER: S-EPMC10123265 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature