Gene network profiling in muscle-invasive bladder cancer: A systematic review and meta-analysis.

ABSTRACT:

Background

Determining meta-analysis of transcriptional profiling of muscle-invasive bladder cancer (MIBC) through Gene Expression Omnibus (GEO) datasets has not been investigated. This study aims to define gene expression profiles in MIBC and to identify potential candidate genes and pathways.

Objectives

To review and evaluate gene expression studies in MIBC through publicly available RNA sequencing (RNA-Seq) and microarray data in order to identify potential prognostic and therapeutic targets for MIBC.

Methods

A systematic literature search of the Ovid MEDLINE, PubMed, and Wiley Cochrane Central Register of Controlled Trials databases was performed using the terms "gene," "gene expression," and "bladder cancer" January 1, 1990 through March 2021 focused on populatio

SUBMITTER: Isali I 

PROVIDER: S-EPMC10123538 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature