Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) can involve persistence, sequelae, and other clinical complications that last weeks to months to evolve into long COVID-19. Exploratory studies have suggested that interleukin-6 (IL-6) is related to COVID-19; however, the correlation between IL-6 and long COVID-19 is unknown. We designed a systematic review and meta-analysis to assess the relationship between IL-6 levels and long COVID-19.

Methods

Databases were systematically searched for articles with data on long COVID-19 and IL-6 levels published before September 2022. A total of 22 published studies were eligible for inclusion following the PRISMA guidelines. Analysis of data was undertaken by using Cochran's Q test and the Higgins I-squared (I²) statistic for he

SUBMITTER: Yin JX 

PROVIDER: S-EPMC10123579 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature