Molecular Tumor Boards: The Next Step towards Precision Therapy in Cancer Care.

ABSTRACT: The application of molecular tumor profiles in clinical decision making remains a challenge. To aid in the interpretation of complex biomarkers, molecular tumor boards (MTBs) have been established worldwide. In the present study, we show that a multidisciplinary approach is essential to the success of MTBs. Our MTB, consisting of pediatric oncologists, pathologists, and pharmacists, evaluated 115 cases diagnosed between March 2016 and September 2021. If targetable mutations were identified, pharmacists aided in the evaluation of treatment options based on drug accessibility. Treatable genetic alterations detected through molecular testing most frequently involved the cell cycle. For 85% of the cases evaluated, our MTB provided treatment recommendations based on the patient's history and re

SUBMITTER: Liu A 

PROVIDER: S-EPMC10123678 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature