Course of intellectual functioning in schizophrenia and bipolar disorder: a 10-year follow-up study.

ABSTRACT:

Background

Intellectual functioning (IQ) is lower in schizophrenia patients compared to healthy controls, with bipolar patients intermediate between the two. Declines in IQ mark the onset of schizophrenia, while stability is generally found post-onset. There are to date few studies on long-term IQ development in bipolar disorder. This study presents 10-year follow-up data on IQ, including premorbid IQ estimates, to track the developmental course from pre-onset levels to long-term outcomes in both patient groups compared to healthy controls.

Methods

We included 139 participants with schizophrenia, 76 with bipolar disorder and 125 healthy controls. Mixed model analyses were used to estimate developmental slopes for IQ scores from estimated premorbid level (NART IQ) through bas

SUBMITTER: Flaaten CB 

PROVIDER: S-EPMC10123835 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature