Modifiable risk factors in women at high risk of breast cancer: a systematic review.

ABSTRACT:

Background

Modifiable risk factors (alcohol, smoking, obesity, hormone use, and physical activity) affect a woman's breast cancer (BC) risk. Whether these factors affect BC risk in women with inherited risk (family history, BRCA1/2 mutations, or familial cancer syndrome) remains unclear.

Methods

This review included studies on modifiable risk factors for BC in women with inherited risk. Pre-determined eligibility criteria were used and relevant data were extracted.

Results

The literature search resulted in 93 eligible studies. For women with family history, most studies indicated that modifiable risk factors had no association with BC and some indicated decreased (physical activity) or increased risk (hormonal contraception (HC)/menopausal hormone therapy (MHT), smoki

SUBMITTER: Cohen SY 

PROVIDER: S-EPMC10123992 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature