Healthcare utilisation and costs associated with adherence to antipsychotics among people living with HIV/AIDS and schizophrenia: a population-based cohort study in British Columbia, Canada.

ABSTRACT:

Objectives

Non-adherence to antipsychotics is the greatest obstacle to treating schizophrenia. We assessed the economic and clinical impacts of adherence to antipsychotics among people living with HIV/AIDS (PLWH) and schizophrenia in British Columbia, Canada.

Design and setting

A population-based cohort study in British Columbia, Canada.

Methods

Eligible PLWH were enrolled in the Seek and Treat for Optimal Prevention HIV/AIDS population-based cohort during 2001-2016, diagnosed with schizophrenia, on antipsychotics for ≥1 day, and followed for ≥1 year from schizophrenia diagnosis date or 1 January 2001, whichever occurred last.

Primary and secondary outcome measures

A two-part model assessed the marginal effect of adherence on healthcare costs (in 2016 Canadian

SUBMITTER: Subedi S 

PROVIDER: S-EPMC10124256 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature