Association of lactate detection with in-hospital mortality in critically ill patients with acute myocardial infarction: a retrospective cohort study.

ABSTRACT:

Objectives

To assess the associations of lactate level or lactate clearance at different time points with in-hospital mortality in critically ill patients with acute myocardial infarction (AMI).

Design

A cohort study.

Setting

The Medical Information Mart for Intensive Care III database.

Participant

490 AMI patients.

Intervention

None.

Primary and secondary outcome measures

In-hospital mortality of patients.

Results

In total, 120 (24.49%) patients died at the end of follow-up. After adjusting for confounders, increased risk of in-hospital mortality in patients with AMI was observed in those with high lactate level (24 hours) (HR=1.156, 95%CI: 1.002 to 1.333). Increased lactate clearance (24 hours) was correlated with a decreased risk of in-h

SUBMITTER: Li H 

PROVIDER: S-EPMC10124257 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature