Seroprevalence of antibodies to herpes simplex virus 1 and 2 in patients with HIV positive from Ebonyi State, Nigeria: a cross-sectional study.

ABSTRACT:

Objectives

To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.

Design

Cross-sectional design from January to June 2019.

Setting

Federal Teaching Hospital, Ebonyi State, Nigeria.

Participants

A total of 276 patients with HIV were analysed using ELISA method for the presence of HSV-1 and HSV-2 specific IgG antibodies.

Outcomes

Fisher's exact test was used to determine the association between the seroprevalence of HSV and demographic variables (statistically significant=p value ≤0.05).

Results

Totally, 212 (76.8%) and 155 (56.2%) patients with HIV were seropositive for HSV-1 and HSV-2 IgG antibodies, respectively. The seroprevalence of HSV-1 was significantly higher than the HSV-2 in pati

SUBMITTER: Onu EN 

PROVIDER: S-EPMC10124271 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature