Symptoms and signs of lung cancer prior to diagnosis: case-control study using electronic health records from ambulatory care within a large US-based tertiary care centre.

ABSTRACT:

Objective

Lung cancer is the most common cause of cancer-related death in the USA. While most patients are diagnosed following symptomatic presentation, no studies have compared symptoms and physical examination signs at or prior to diagnosis from electronic health records (EHRs) in the USA. We aimed to identify symptoms and signs in patients prior to diagnosis in EHR data.

Design

Case-control study.

Setting

Ambulatory care clinics at a large tertiary care academic health centre in the USA.

Participants, outcomes

We studied 698 primary lung cancer cases in adults diagnosed between 1 January 2012 and 31 December 2019, and 6841 controls matched by age, sex, smoking status and type of clinic. Coded and free-text data from the EHR were extracted from 2 years prior

SUBMITTER: Prado MG 

PROVIDER: S-EPMC10124310 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature