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Outcome domains reported in calcium pyrophosphate deposition studies: A scoping review by the OMERACT CPPD working group.


ABSTRACT:

Introduction

Although calcium pyrophosphate deposition (CPPD) is common, there are no validated outcome domains and/or measurements for CPPD studies. The aim of this work was to identify domains that have been reported in prior clinical studies in CPPD, to inform the development of a core set of domains for CPPD studies.

Methods

We performed a scoping literature review for clinical studies in CPPD, searching in Medline (via PubMed), EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) databases; published from January 1, 1946 to January 7, 2020. All reported outcomes and study design data were extracted and mapped to the core areas and domains as defined by the OMERACT Filter 2.1.The protocol was registered on PROSPERO (CRD: 42019137075; 09-07-2019).

Findi

SUBMITTER: Cai K 

PROVIDER: S-EPMC10124328 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature