Diabetes and Progression of Heart Failure: The Atherosclerosis Risk In Communities (ARIC) Study.

ABSTRACT:

Background

The influence of diabetes on progression from preclinical heart failure (HF) stages to overt HF is poorly understood.

Objectives

The purpose of this study was to characterize the influence of diabetes on the progression from preclinical HF stages (A or B based on the 2021 Universal Definition) to overt HF.

Methods

We included 4,774 adults with preclinical HF (stage A [n = 1,551] or B [n = 3,223]) who attended the ARIC (Atherosclerosis Risk In Communities) study Visit 5 (2011-2013). Within each stage (A or B), we assessed the associations of diabetes and glycemic control (hemoglobin A_1C [HbA_1C] <7% vs ≥7%) with progression to HF, and of cross-categories of HF stages (A vs B), diabetes, and glycemic control with incident HF.

Results</

SUBMITTER: Echouffo-Tcheugui JB 

PROVIDER: S-EPMC10125541 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature