Topical hemostatic agents in the management of upper gastrointestinal bleeding: a meta-analysis.

ABSTRACT: Background and study aims  Novel topical hemostatic agents have shown promising results in treating patients with non-variceal upper gastrointestinal bleeding (NVUGIB). However, data are limited even in published meta-analyses as to their role, especially compared to conventional endoscopic approaches. The aim of this study was to perform a highly comprehensive systematic review assessing the effectiveness of topical hemostatic agents in UGIB in different clinical settings. Methods  We performed a literature search of OVID MEDLINE, EMBASE, and ISI Web of Knowledge databases through September 2021. Studies assessing the efficacy of topical hemostatic agents in UGIB were included. Main outcomes were immediate hemostasis and overall rebleeding. Results  A total of 980 cit

SUBMITTER: Alali AA 

PROVIDER: S-EPMC10125779 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature