MethylR: a graphical interface for comprehensive DNA methylation array data analysis.

ABSTRACT:

Motivation

DNA methylation analysis using arrays is a widely used method in research and clinical studies to study Epigenetics. Although several packages have been published to incur the results, most of them require a deep computational knowledge to perform the analysis. To resolve the limitation and to offer an easily accessible solution for researchers, we developed methylR a graphical tool that can analyze not only the raw data but also performs different downstream analyses with a few mouse clicks.

Results

We used standard and established open-source published packages or pipelines in methylR. We evaluated a publicly available dataset and compared the published results with those obtained with our tool. We implemented eight downstream analysis modules that can perform m

SUBMITTER: Volpe M 

PROVIDER: S-EPMC10125902 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature