Novel device for dividing core needle biopsy specimens to provide paired mirror image-like tissues for genetic and pathological tests.

ABSTRACT: In a world that seeks precision medicine, genetic testing is gaining importance in clinical decision making. We previously reported the utility of a novel tool for longitudinally dividing core needle biopsy (CNB) tissues into two filamentous tissues that can provide paired mirror image-like tissues (mirror-tissues) that spatially match each other. In this study, we investigated its application in gene panel testing in patients who underwent prostate CNB. Four hundred and forty-three biopsy cores were obtained from 40 patients. Of them, 361 biopsy cores (81.5%) were judged by a physician to be appropriate for dividing into two pieces using the new device, of which a histopathological diagnosis was successfully reached in 358 biopsy cores (99.2%). Among them, the quality and quantity of nucl

SUBMITTER: Nakamura Y 

PROVIDER: S-EPMC10126131 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature