Digital adherence technologies to improve tuberculosis treatment outcomes in China: a cluster-randomised superiority trial.

ABSTRACT:

Background

Drug-sensitive tuberculosis treatment requires 6 months of therapy, so adherence problems are common. Digital adherence technologies might improve tuberculosis treatment outcomes. We aimed to evaluate the effect of a daily reminder medication monitor, monthly review of adherence data by the health-care provider, and differentiated care for patients with adherence issues, on tuberculosis treatment adherence and outcomes.

Methods

We did a cluster-randomised superiority trial across four prefectures in China. 24 counties or districts (clusters) were randomly assigned (1:1) to intervention or control groups. We enrolled patients aged 18 years or older with GeneXpert-positive, rifampicin-sensitive pulmonary tuberculosis, who were receiving daily fixed-dose combination

SUBMITTER: Liu X 

PROVIDER: S-EPMC10126227 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature