Epidemiological trends for functional pancreatic neuroendocrine tumors: A study combining multiple imputation with age adjustment.

ABSTRACT:

Purpose

The purpose of this study was to examine trends in the incidence and incidence-based (IB) mortality of functional pancreatic neuroendocrine tumors(F-PNETs), and to identify factors associated with survival times.

Methods

Data were obtained from the Surveillance, Epidemiology, and End Results database from 2000 to 2017. Trends in the age-adjusted incidence of F-PNETs and IB mortality were examined using the Joinpoint Regression Program. Statistical analyses were run using chi-square tests, Kaplan-Meier curves, and the Cox proportional hazards model. Multiple imputation was used to deal with missing data.

Results

A total of 142 patients with F-PNETs met the study inclusion criteria. It was found that the incidence of F-PNETs decreased over the study period, with

SUBMITTER: Luo S 

PROVIDER: S-EPMC10126336 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature