A CaCuSi₄O₁₀/GCE electrochemical sensor for detection of norfloxacin in pharmaceutical formulations.

ABSTRACT: This study reports on a calcium copper tetrasilicate (CaCuSi₄O₁₀)/glassy carbon electrode (GCE) electrochemical sensor developed for rapid sensing and quantification of an antibacterial drug, norfloxacin, using both cyclic voltammetry and differential pulse voltammetry. The sensor was fabricated by modifying a glassy carbon electrode with the CaCuSi₄O₁₀. Electrochemical impedance spectroscopy was performed and the Nyquist plot showed that the CaCuSi₄O₁₀/GCE had a lower charge transfer resistance of 22.1 Ω cm² compared to the GCE with a charge transfer resistance of 43.5 Ω cm². Differential pulse voltammetry showed that the optimum pH for the electrochemical detection of norfloxacin in potassium phosphat

SUBMITTER: Muungani G 

PROVIDER: S-EPMC10126821 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature