The role of aldosterone and ideal cardiovascular health in incident cardiovascular disease: The Jackson heart study.

ABSTRACT:

Background

Higher levels of ideal cardiovascular health (ICH) are associated with lower levels of aldosterone and incidence of cardiovascular disease (CVD). However, the degree to which aldosterone mediates the association between ICH and CVD incidence has not been explored. Thus, we investigated the mediational role of aldosterone in the association of 5 components of ICH (cholesterol, body mass index (BMI), physical activity, diet and smoking) with incident CVD and the mediational role of blood pressure (BP) and glucose in the association of aldosterone with incident CVD in a cohort of African Americans (AA).

Methods

The Jackson Heart Study is a prospective cohort of AAs adults with data on CVD outcomes. Aldosterone, ICH metrics and baseline characteristics were collected

SUBMITTER: Kluwe B 

PROVIDER: S-EPMC10126856 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature